Quality of randomised controlled trials in head injury. Trials in head injury are more complex than review suggests.
نویسندگان
چکیده
منابع مشابه
Epidemiologic study of fall-related head injury in Iran and its comparison with other countries: review article
Head injury is one of the most important types of injury and is responsible for most of the deaths due to trauma. Low-income and middle-income countries face with more risk factors, but they still lack adequate health-care capacity to deal with complications. Trauma literally means the damage and injury, and head injury was defined as physical damage to the brain or skull caused by external for...
متن کاملSize and quality of randomised controlled trials in head injury: review of published studies.
OBJECTIVE To assess whether trials in head injury are large enough to avoid moderate random errors and designed to avoid moderate biases. DESIGN All randomised controlled trials on the treatment and rehabilitation of patients with head injury published before December 1998 were surveyed. Trials were identified from electronic databases, by hand searching journals and conference proceedings, a...
متن کاملReview: mild induced hypothermia does not reduce mortality or severe disability in moderate to severe head injury.
Study selection and assessment: randomised controlled trials (RCTs) that compared mild therapeutic hypothermia (local or systemic therapeutic cooling [using a fluid filled cooling blanket, a ‘‘Bear Hugger’’ air cooling device, ice water lavage, or combination, or other method] to a target temperature (34– 35 C̊ for >12 hours beginning on admission to the intensive care unit or when intracranial ...
متن کاملEffect of nimodipine on outcome in patients with traumatic subarachnoid haemorrhage: a systematic review.
BACKGROUND Despite several randomised controlled trials, there is still much debate whether nimodipine improves outcome in patients with traumatic subarachnoid haemorrhage. A 2003 Cochrane review reported improved outcome with nimodipine in these patients; however, because the results of Head Injury Trial (HIT) 4 were only partly presented there is still discussion whether patients with traumat...
متن کاملNeglected tropical diseases: survey and geometry of randomised evidence
OBJECTIVE To assess the quantity and distribution of evidence from randomised controlled trials for the treatment of the major neglected tropical diseases and to identify gaps in the evidence with network analysis. DESIGN Systematic review and network analysis. DATA SOURCES Cochrane Central Register of Controlled Trials and PubMed from inception to 31 August 2011. STUDY SELECTION Randomis...
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عنوان ژورنال:
- BMJ
دوره 321 7270 شماره
صفحات -
تاریخ انتشار 2000